We went 3 weeks between Pisa and Naples through Tuscany and Rome during July-August 2016.
We did this tour using mainly trains with our 2 kids (7 and 10 years old). It went very well.
We went 3 weeks in Sicily during July-August 2013.
We rent a car. The travel went well with our 2 kids (4 and 7 years old).
We went in Venice while a long week end in November 2010.
Even the city has become a giant museum, it stays unique and nice picture sight
We booked an hotel close to San Marco Place and Canale Grande. Quite convenient ! We particuliarly appreciated the breakfasts in front of Canale Grande...